The INTerpath-001 trial is evaluating Moderna/Merck’s mRNA-4157 in combination with Merck’s Keytruda A phase 3 international trial evaluating a new personalised immunotherapy treatment for
Medicine
Cambridge researchers develop robotic nerve devices for neurological conditions
Neurological disorders, such as epilepsy or chronic pain, affect over three billion people worldwide Researchers at the University of Cambridge have developed small, flexible
Silent plight – PharmaTimes
Despite ever increasing funding, clinical trials in primary biliary cholangitis (PBC) continue to struggle. PBC is an often silent, rare disease which means recruitment
Study reveals vitamin D-altered mouse gut bacteria provides better cancer immunity
Bacteroides fragilis in the gut improves immunity and immunotherapy treatment responses Researchers from the Francis Crick Institute, the National Cancer Institute of the US
Nova’s Xromi approved in UK and EU for vaso-occlusive complications of SCD
The inherited disorder is caused by genetic mutations that affects haemoglobin production Nova Laboratories’ Xromi (hydroxycarbamide) has received approval from the Medicines and Healthcare
Study finds mechanical changes in tumour tissue offer new insights for cancer research
Bladder cancer, including papillary tumours, is the ninth most common cancer type worldwide Researchers from ETH Zurich and University Hospital Basel have revealed new
Cambridge researchers use AI to accelerate drug design for Parkinson’s disease
The progressive neurological condition affects more than six million people worldwide Researchers from the University of Cambridge have designed and used an artificial-intelligence (AI)-based
MIT researchers find circadian rhythms in liver function influence drugs’ effectiveness
An estimated 50% of human genes follow a circadian cycle, many of which are active in the liver A new study conducted by researchers
Cambridge study finds AI more accurately assesses eye problems compared to doctors
GPT-4 is trained on datasets to offer eye-related advice, diagnosis and management suggestions A new study led by researchers from the University of Cambridge
Alex Livingstone-Learmonth – PharmaTimes
Cambridge Cognition has announced Alex Livingstone-Learmonth as CCO Cambridge Cognition has announced the appointments of Alex Livingstone-Learmonth as Chief Commercial Officer and Annabelle Miles
Helen Dent – PharmaTimes
British In Vitro Diagnostic Association has appointed Helen Dent as Chief Executive The British In Vitro Diagnostic Association (BIVDA) has appointed Helen Dent as
Boehringer Ingelheim and Ochre Bio partner on liver disease in deal worth over $1bn
Chronic liver disease and associated cirrhosis account for one million deaths every year Boehringer Ingelheim and Ochre Bio have partnered to discover and develop
Two RNA-binding proteins could contribute to cancer therapy development
The paper identifies the roles and differences between LARP4A and LARP4B in sarcoma and carcinoma cancers A Medical Research Council doctoral training partnership (MRC-DTP)
Bridging the gap – PharmaTimes
The key to a culture-conscious pharma partnership Partnerships are not just about expanding our reach and product portfolio, but also about creating a powerful
Scientists reveal new method that could reduce waste from drug manufacturing
The new method could help to prevent severe side effects caused by enantiomer drugs Scientists from the University of Edinburgh’s School of Chemistry have
MPE launches English Myeloma and AL Amyloidosis European Clinical Trial Navigator
The tool will help people find out about clinical trials for myeloma, MGUS, SMM and AL amyloidosis Myeloma Patients Europe (MPE) has launched the
CMT Research Foundation funds study investigating treatment for CMT1X disease
X-linked Charcot-Marie-Tooth is the second most common form of the rare peripheral neuropathy disease The CMT Research Foundation (CMTRF) has invested in a study
New heart disease calculator more accurately predicts patients’ risk of CVDs
According to the World Health Organization, CVDs are responsible for an estimated 17.9 million deaths every year Researchers from the universities of Oxford, Nottingham
UCL study to assess link between navigation and AD using virtual reality
The progressive neurodegenerative condition is the most common form of dementia Researchers from University College London (UCL) have begun recruiting volunteers to assess the
Trial reveals mechanisms that contribute to impact of malnutrition and HIV infection
Severe acute malnutrition is responsible for nearly half of all child deaths globally and affects 17 million children annually A trial led by researchers
Green giants
The rise of pharmacies and their new role in primary healthcare
Study links dementia antipsychotics to higher risks of serious health outcomes
The neurodegenerative condition currently affects more than 944,000 people living in the UK Researchers from the Universities of Manchester, Nottingham, Edinburgh and Dundee have
New NIHR HRC launched for cardiovascular and respiratory medicine
The launch is part of the NIHRs £42m funding to establish 14 new HRCs across England Guy’s and St Thomas’ and King’s College London
Ifs, bots and maybes
Our future robot overlords are playing the long game
CureVac and MD Anderson Cancer Center partner to develop new cancer vaccines
Both will develop cancer vaccine candidates in selected haematological and solid tumour indications CureVac and the University of Texas’s MD Anderson Cancer Center have
New clinical trial aims to investigate skin patches to spot lung transplant rejection
Involving 152 patients, the SENTINEL trial aims to cut lung transplant rejection by up to 50% A new clinical trial being led by the
New UK report highlights inequalities among people living with breast cancer
Breast cancer was responsible for 2.3 million diagnoses and 670,000 deaths globally in 2022 A new report led by the University of Cambridge and
Researchers introduce new AI tool to help clinicians capture uncertainty in medical images
The Tyche model could help clinicians and researchers capture crucial information in images Researchers from the Massachusetts Institute of Technology (MIT), the Broad Institute
Study reveals how specific nasal cells protect against COVID-19 in paediatric patients
The findings suggest why children tend to experience milder symptoms compared to older adults Researchers from University College London (UCL) and the Wellcome Sanger
ELRIG UK and SRG collaborate to advance life sciences professionals in drug discovery
Both companies will facilitate career progression while advancing the life sciences industry The European Laboratory Research and Innovation Group (ELRIG) UK has announced its
Bio-Rad and Oncocyte partner to develop and commercialise transplant monitoring products
Solid organ transplantation is used to treat end-stage organ failure, including the kidneys Bio-Rad Laboratories and Oncocyte Corporation have partnered to develop and commercialise
UCL study reveals carbon beads could help reduce progression of liver disease
Liver cirrhosis, caused by long-term liver damage, is estimated to affect around 100 million people worldwide Researchers from University College London (UCL) have invented
Nine UCL researchers secure £560m in research funding from ERC
Approximately 14% of the competition-submitted proposals were selected to receive funding Nine researchers from University College London (UCL) have secured nearly £560m in funding
Francis Crick researchers reveal pathways linking intestinal inflammation and colitis
Affecting over 500,000 people in the UK, IBD comprises Crohn’s disease and ulcerative colitis The study, published in Nature Immunology, could help identify new
Study suggests tumour microenvironments could predict cancer progression
NSCLC is the most common type of lung cancer and is responsible for up to 85% of all cases Researchers from the Francis Crick
KCL and McMaster University partner to advance nuclear medicine research
Both partners’ will leverage their nuclear research facilities and expertise to develop new health interventions King’s College London’s (KCL) Biomedical Engineering and Imaging Sciences
Driving transformation – PharmaTimes
In today’s rapidly evolving healthcare landscape, transformation is key to success and medical affairs teams play a vital role in making it happen. But
UK study finds screening with a PSA test in prostate cancer can lead to overdiagnosis
Prostate cancer is responsible for around 12,000 deaths a year in the UK and is the second biggest cause of death for men Researchers
Researchers call to reduce repeat antibiotic prescriptions for respiratory tract infections
RTIs account for around 60% of global antibiotic prescribing and are a key driver of AMR Researchers from the Universities of Bristol, Bath, King’s
Bio-Rad and Alleghany Health Network partner for patients with solid tumour cancer
Solid tumour cancers account for 90% of adult human cancers and 50% of childhood malignancies Bio-Rad Laboratories and Alleghany Health Network (AHN) have partnered
Study reveals shorter scans for prostate cancer could improve diagnosis
The most common form of cancer in men is responsible for 12,000 deaths every year in the UK A clinical trial led by researchers
Culmination Bio and BillionToOne partner to advance cancer diagnosis
Both will validate the clinical performance of two new diagnostic tests for regulatory submission Culmination Bio has announced a partnership with BillionToOne to develop
US researchers reveal positive results of personalised vaccine for liver cancer
Hepatocellular carcinoma is one of the leading causes of cancer-related deaths worldwide Researchers from the Johns Hopkins Kimmel Cancer Center and its Convergence Institute
Alliance Healthcare launches cancer symptom referral scheme in UK pharmacies
Around three million people in the UK were estimated to be living with cancer in 2022 Alliance Healthcare has announced it has opened access
Unitaid funds over £6m to Liverpool researchers to treat major diseases
The project aims to advance therapeutics for tuberculosis, malaria and hepatitis C in LMICs A research project led by the University of Liverpool has
myTomorrows and brainstrust partner to support patients living with brain cancer
Affecting 80,000 people in England, 12% of brain tumour patients survive beyond five years of diagnosis myTomorrows has announced a new partnership with a
Key mechanism controlling bone marrow stem cells could lead to new therapies
Hoxa9 and b-catenin molecules are a rare population of self-renewing HSCs found in bone marrow Researchers from King’s College London’s (KCL) Comprehensive Cancer Centre
Study reveals new aptamer targeting tool can detect early signs of motor neurone disease
The fatal, progressive neurological condition currently affects around 5,000 people in the UK Researchers from the University of Edinburgh and the University of Aberdeen
KCL project receives £100,000 UK government funding to boost AI-assisted healthcare
The project will assist researchers and companies in training the technology for healthcare settings A project being led by King’s College London (KCL) has
Researchers suggest form of Alzheimer’s is transmissible via bone marrow transplants
The progressive neurodegenerative disease is estimated to affect 24 million people globally Researchers from the University of British Columbia in Canada have revealed that
Study reveals new liquid biopsy test could benefit thousands of lung cancer patients
The third most common and serious form of cancer affects over 43,000 people every year in the UK In partnership between The Royal Marsden
Researchers reveal people with Parkinson’s more likely to experience delirium in hospital
Two out of three people with the neurodegenerative condition experienced delirium in hospital Researchers from Newcastle University have revealed that people living with Parkinson’s
Collaborators form national NHS patient database registry for Lynch syndrome patients
The genetic condition affects one in 279 people in England and significantly increases cancer risk Researchers from the Institute of Cancer Research (ICR), in
Andrew Caldwell – PharmaTimes
Amylyx has appointed Andrew Caldwell as General Manager UK and Ireland Amylyx has announced the appointment of Andrew Caldwell as General Manager UK and Ireland. He joins the company
Paul Adams – PharmaTimes
Paul Adams is new Chief Executive Officer of LloydsPharmacy Clinical Homecare Paul Adams has been announced as the new Chief Executive Officer of LloydsPharmacy Clinical Homecare,
Irina Spirieva – PharmaTimes
Besins has appointed Irina Spirieva as General Manager for UK and Ireland Besins Healthcare has announced the appointment of Irina Spirieva as its new General Manager for
PMLiVE’s T40 – open for submissions!
Healthcare agencies can submit their entries free of charge with a deadline of 30 April The 2024 edition of PMLiVE’s T40 list of creative
University of Liverpool to lead £125m research facility supported by UKRI investment
Set to open in 2032, the RUEDI facility is funded by the UKRI’s recent infrastructure fund worth £388m The University of Liverpool has announced
Strand Therapeutics develops new class of mRNA molecules for cancer
The self-replicating mRNA molecule could be used in cancer and potentially a broad range of other diseases Strand Therapeutics, a Massachusetts Institute of Technology
PhaSER Biomedical and the Sanders TDI partner for clinical drug discovery research
PhaSER will provide 8HUM mouse models for the TDI to accelerate a pipeline of novel therapeutic targets PhaSER Biomedical has announced its long-term partnership
LifeArc provides £750,000 fund for clinical trial to treat neuroferritinopathy
The progressive and incurable brain disorder currently affects approximately 100 patients worldwide LifeArc has announced that it has funded a pivotal clinical trial at
Ioana Parsons – PharmaTimes
Ipsen has appointed Ioana Parsons as General Manager UK & Ireland Ipsen has announced the appointment of Ioana Parsons as General Manager of the company’s UK & Ireland affiliate.
This time it’s personal – PharmaTimes
Clinical trials, the cornerstone of medical advancement, have stood largely unchanged over the past two decades. An evolution has begun, however, indicating a future
Skin biopsy test detects abnormalities of key biomarker in neurodegenerative disorders
Estimated to affect 2.5 million people in the US, synucleinopathies comprise four neurodegenerative disorders Neurologists from the Beth Israel Deaconess Medical Center (BIDMC) have
Francis Crick researchers target cancer cells’ ability to survive at low oxygen levels
LDHA and GOT1 enzymes successfully targeted and halted energy production in hard-to-reach cancer cells Researchers from the Francis Crick Institute have revealed how cancer
Green cross code
Unleashing the potential of pharmacies through Pharmacy First
Innovate UK awards ten projects over £6m to develop new clinical tools for dementia
Dementia is estimated to affect 850,000 people in the UK and costs the nation around £23bn a year Innovate UK has awarded ten new
Four international teams awarded £4.7m to investigate heart and circulatory diseases
These types of conditions are responsible for 25% of all UK deaths and affect 7.6 million people nationally The British Heart Foundation (BHF), the
Ceiling smashers
We need more women in pharma and life sciences
Parkinson’s UK grants funding of up to nearly £450,000 to four new research projects
The globally fast-growing progressive neurological condition affects around 153,000 people in the UK Parkinson’s UK has announced that it is funding four new research
Researchers reveal protein found in human sweat could protect against Lyme disease
The bacterial infection transmitted by ticks affects nearly half a million people in the US every year Researchers from the Massachusetts Institute of Technology
Researchers suggest treatments for rare diseases could reduce burden of kidney disease
Rare kidney diseases are a group of conditions which account for over 5% of people living with chronic kidney disease A new study led
New study reveals neurological conditions as leading cause of ill health worldwide
In 2021, neurological conditions, including Alzheimer’s disease, affected approximately 3.4 billion people globally In a new study funded by the Bill & Melinda Gates
ALS Association partners with myTomorrows to improve clinical trial accessibility
The fatal motor neurone disease currently does not have a cure available to treat patients The ALS Association and myTomorrows have partnered to improve
KCL researchers develop pipeline to create customisable cell culture device creations
The SOL3D pipeline addresses research challenges in relation to equipment, expertise and cost Scientists from King’s College London’s (KCL) UK Dementia Research Institute’s (UK
AZ/Merck’s Lynparza approved by SMC to treat advanced prostate cancer in Scotland
Up to 20% of prostate cancer cases are classified as castration-resistant AstraZeneca (AZ) and Merck & Co – known as MSD outside the US
Birmingham’s VR-assisted training centre for excellence to support future vaccine makers
The centre will deliver free training, outreach materials and programmes The University of Birmingham is set to lead UK-wide virtual reality (VR)-assisted training in
Swedish researchers develop new AI computer model to detect lymphatic cancer
In the study, the Lymphoma Artificial Reader System accurately detected 90% of lymphatic cancers Researchers from Chalmers University of Technology in Sweden have developed
Roche partners with Cardiff researchers to uncover new research into dementia
Affecting 55 million people globally, dementia impairs the ability to remember, think or make decisions Roche and the Cardiff University Brain Research Imaging Centre
NHS to roll out AI to improve waiting times and reduce missed appointments
Every year, missed hospital appointments are estimated to cost the NHS £1.2bn The NHS has announced that it’s set to roll out artificial intelligence
NIHR reveals phase 1/2 trial to evaluate an investigational vaccine for mpox in the UK
More than 3,700 cases of mpox have been identified in the UK since May 2022 The National Institute for Health and Care Research (NIHR)
Deal or no deal
Approaches to M&As in pharma points to each company’s philosophy
Amy Greenwood – PharmaTimes
Stirred has revealed that Amy Greenwood will lead ‘Stirred Well’ Stirred has announced the arrival of former Evoke consumer health director, Amy Greenwood, to lead its new
AbbVie’s Produodopa approved by SMC to treat Parkinson’s disease patients in Scotland
The progressive neurological disorder affects approximately 12,400 people in Scotland AbbVie’s Produodopa (foslevodopa-foscarbidopa) has been accepted by the Scottish Medicines Consortium (SMC) for use
US study reveals age-related skin changes could contribute to melanoma metastases
Around 200,000 people in the US are expected to be diagnosed with the skin cancer this year Researchers from the Johns Hopkins Kimmel Cancer
ICR awarded $25m by Cancer Grand Challenges to research solid tumours in children
Globally, cancer is currently the most leading cause of death due to disease among children The Institute of Cancer Research (ICR) has announced it
NHS campaign urges over 900,000 young adults to catch up on missed MMR vaccine
Between October 2023 and March 2024, the UKHSA said that 733 cases of measles were reported in England The NHS has announced it is
KCL joins new project launched by European consortium to improve newborn health
The HYPIEND project consists of 14 partners from eight European countries King’s College London (KCL) has announced that it is one of 14 partners
Study reveals children with amblyopia are at higher risk of serious disease in adulthood
The neurodevelopmental condition affects up to four in 100 children A new study led by researchers at University College London (UCL) and other collaborators
MIT study reveals non-invasive treatment holds promise for treating ‘chemo brain’
The gamma treatment also shows potential for treating patients living with neurological diseases Researchers from the Massachusetts Institute of Technology (MIT) have shown that
MHRA approves Marinus Pharmaceuticals’ Ztalmy for CDKL5 deficiency disorder
The rare epileptic seizure disorder currently affects around one in 42,000 people in the UK The Medicines and Healthcare products Regulatory Agency (MHRA) has
NHS to ensure people eligible for very high-risk breast screening are referred
Secondary breast cancer is an important risk factor after receiving radiotherapy for Hodgkin lymphoma NHS England has responded to the recent ministerial statement by
US researchers develop algorithm test to identify aggressive ovarian cancers
Ovarian high-grade serous carcinoma is the most common form of aggressive ovarian cancer Researchers from Johns Hopkins Kimmel Cancer Center and the Johns Hopkins
Researchers aim to ensure future AI healthcare monitoring systems are free of gender bias
The project will train a newly developed AI system on data collected from participating men and women Researchers from the University of Glasgow’s James
Researchers use collected stem cells to grow cell models to advance prenatal medicine
CDH affects one in 5,000 babies born in the UK, impacting the foetus’ development of vital organs Researchers from University College London (UCL) and
Researchers develop brain-age prediction tool for diagnosis of neurological diseases
The non-invasive tool can also improve patient stratification and monitor disease progression Researchers from King’s College London (KCL) have developed a deep learning framework
Womb condition checks could reduce cancer risk in endometrial hyperplasia
Women with atypical endometrial hyperplasia have an increased risk of developing cancer Researchers from the University of Edinburgh have revealed that improved patient care
Poor spatial navigation could predict Alzheimer’s before symptom onset
Around 900,000 people in the UK are affected by the progressive neurodegenerative disease Researchers from University College London (UCL), in collaboration with the University
Researchers reveal two different subtypes of prostate cancer using AI
In the UK alone, the aggressive form of cancer affects around 52,000 men every year Researchers from the University of Oxford and the University
New digital iTalkBetter app significantly improves speech in stroke patients
Aphasia is a language disorder caused by some form of brain damage, including stroke Researchers from the Neurotherapeutics Group at University College London’s Queen
ICL uses AI to help doctors assess lung cancer from ‘virtual biopsies’
TMR-CT will help doctors select treatment and predict the spread of lung cancer in patients Imperial College London (ICL) researchers have used artificial intelligence
Researchers reveal COVID-19 could have small impacts on cognition and memory
Different factors, such as illness duration and virus variant, impacted patients cognitive abilities Imperial College London (ICL) researchers have revealed that people who have
‘Top-down’ treatment strategy dramatically improves outcomes for Crohn’s patients
Approximately 80% of patients taking Remicade from diagnosis had symptoms controlled Researchers from the University of Cambridge have revealed a ‘top-down’ treatment strategy involving
Leap of faith – PharmaTimes
In 2024, Rare Disease Day falls on an appropriately rare calendar date: 29 February, a leap year. This international awareness campaign provides the perfect opportunity to highlight the
ICR study reveals new targeted immunotherapy to prevent spread of breast cancer
Breast cancer is responsible for around 47,000 new cases in England every year Researchers from the Institute of Cancer Research (ICR) have revealed a
Reusable ECGI vest successfully detects early signs of inherited hypertrophic cardiomyopathy
The inherited fatal heart muscle condition affects one in every 500 adults in the UK Researchers from University College London (UCL) have developed a
Sponge-on-a-string test to benefit NHS patients with oesophageal cancer
Eight out of ten patients who took the test were discharged without needing further testing The NHS has announced that a simple sponge-on-a-string test
UK and Netherlands researchers call for funding to investigate cancer treatments
The white paper outlines three strategic recommendations to support further research Researchers from King’s College London and Erasmus MC in the Netherlands have called
PhaSER Biomedical receives $2.3m drug discovery grant from the Gates Foundation
Every year, tuberculosis, malaria and HIV cause over five million deaths worldwide PhaSER Biomedical has received a grant from the Bill & Melinda Gates
Awaken the giant within – PharmaTimes
Why haven’t we been delivering more life sciences research in primary care? Since the COVID-19 pandemic there has been an increasing recognition that primary
Rise of the organoids – PharmaTimes
Growing cerebral organoids from foetal human brain tissue For the first time, scientists have grown cerebral organoids from human foetal brain tissue. This is another leap in the
Elicio’s vaccine shows promise as potential cancer treatment in phase 1 trial
Results showed robust responses in patients with pancreatic and colorectal cancer Elicio Therapeutics has announced positive phase 1 clinical data suggesting that its cancer
NHS offers preventative bowel cancer screening for patients with Lynch syndrome
In England, around 1,100 cases of bowel cancer are caused by the inherited condition every year The NHS has announced it is offering routine
AbbVie’s Skyrizi shows promise as personalised treatment for psoriasis
The immunosuppressant reduced inflammation in patients with the skin condition after three days Researchers from King’s College London (KCL) have investigated the early effects
New brain cancer proton beam therapy clinical trial launched in UK
The trial is recruiting patients in Leeds, Manchester, Oxford, London, Cambridge and Kent The University of Leeds has launched a trial funded by the
NHS launches new campaign to help patients get treatment from pharmacies
Pharmacy First will enable patients to receive treatment for seven common conditions The NHS has launched a new campaign to raise awareness of the
Researchers launch global iSPY network to research Strep A infections
A streptococcal bacterial infections are estimated to affect around 50 million people worldwide Researchers from Imperial College London (ICL) and the University of California
Quantum leap – PharmaTimes
For life sciences organisations, the pressure to speed up the time to market of new drugs and therapies continues at pace, alongside the need
Researchers develop nanogel to deliver anti-inflammatory drugs for spinal cord injury
The nanogels, in combination with rolipram, contributed to the recovery of injured tissue Researchers from the Instituto di Ricerche Farmacologiche Mario Negri IRCCS and
New initiative to improve patient retention in paediatric clinical trials
The new programme will engage with children and young people under the age of 18 years Innovative Trials has announced a new initiative designed
Digital CBT reduced distress in patients with long-term physical health conditions
Participants who received COMPASS showed a clinically significant improvement after 12 weeks Researchers from King’s College London’s (KCL) Institute of Psychiatry, Psychology and Neuroscience
Predict-PD study to identify those at high risk of PD before symptoms appear
The study aims to improve the representation of ethnic diversity within Parkinson’s research A study led by researchers at Queen Mary University and University
Neurona secures $120m to advance lead cell therapy candidate for epilepsy
NRTX-1001 is being assessed for drug-resistant mesial temporal lobe epilepsy Neurona Therapeutics has announced that it has secured $120m in funding to help advance
Researchers investigate new technique for diagnosing cardiac conditions
Cardiac quantitative susceptibility mapping successfully visualised iron deposits in patients Researchers from King’s College London (KCL) have investigated a new technique for diagnosing and
Closed Loop Medicine shares results of proprietary technology for hypertension
CLM-HT01 improved blood pressure and minimised adverse reactions in patients Closed Loop Medicine has shared positive results of its novel drug and proprietary technology
Stroke brain-bleed deaths predicted to increase by 40% in the UK
In Europe, stroke-related brain-bleed deaths are expected to increase by 8.9% by 2050 Researchers from King’s College London (KCL) have predicted that the number
New report urges UK policymakers to take urgent action on declining child health
The report includes five recommendations for the government to address these issues The Academy of Medical Sciences has published a new report that highlights
Positive results for MAIA’s SCLC treatment published in Nature Communications
The aggressive type of cancer accounts for 13% of all lung cancer cases worldwide MAIA Biotechnology has announced that positive results from its preclinical
First UK patients receive experimental mRNA therapy for cancer in global trial
The phase 1/2 Mobilize trial is evaluating the safety and efficacy of mRNA-4359 Imperial College Healthcare NHS Trust (ICHT) and Imperial College London (ICL)
NIHR awards over £20m to eight new global health research projects
The projects will focus on healthcare in LMICs in the event of extreme weather The National Institute for Health and Care Research (NIHR) has
Scientists develop micofluidic chip to make cell therapy safer
The chip removes cells, which could become tumours, before they are implanted in a patient Researchers from the Massachusetts Institute of Technology (MIT) and
Phesi’s AI-driven Trial Accelerator platform contains over 100 million patients
The platform delivers digitalised patient data to improve clinical trials and development Phesi has announced that its artificial intelligence (AI)-driven Trial Accelerator platform has
Sarah Jones – PharmaTimes
M+F Health has announced the appointment of Sarah Jones as a Director M+F Health has announced the appointment of Sarah Jones as a Director. Sarah joins the
Chris Grimes-Crompton – PharmaTimes
Decisive Consulting has appointed Chris Grimes-Crompton to its leadership team Decisive Consulting has appointed Chris Grimes-Crompton to lead its global commercial strategy efforts and become a member
Researchers identify new treatment target for genetic epilepsy
The rare neurodevelopmental condition CDKL5 is characterised by early-onset epilepsy Researchers from the Francis Crick Institute have identified a new treatment target for cyclin-dependent
Royal Marsden to implement RaySearch’s online adaptive radiation therapy system
OART is increasingly emerging to assess and adapt treatment for cancer patients The Royal Marsden NHS Foundation Trust is set to implement online adaptive
Researchers discover new type of memory B cell that remembers allergies
The cell could be a target for new immunotherapies for the chronic disease Researchers from McMaster University and the pharmaceutical company ALK-Abello have discovered
JCVI announces advice for 2024 spring COVID-19 vaccine programme
The committee has advised that the vaccine should be given to those at the highest risk The Joint Committee on Vaccination and Immunisation (JCVI)
ALTURiX acquires exclusive UK rights to three new products
The new products are in the areas of gastrointestinal and respiratory medicines ALTURiX has announced that it has acquired exclusive rights to three new
Brainomix’s AI-enabled stroke software endorsed by NICE
The HTA reported that Brainomix 360 improved access to treatment for stroke patients The National Institute of Health and Care Excellence (NICE) has issued
Study reveals blood test can pinpoint cause of brain injury in newborns
Hypoxic-ischaemic encephalopathy affects around three million babies worldwide every year Researchers from Imperial College London have revealed that a blood test can pinpoint the
New heart treatment to help grow replacement heart valves in the body
The biodegradable polymer scaffold encourages the body to grow new tissue Researchers at Harefield Hospital and Imperial College London’s (ICL) National Heart and Lung
Study reveals AI can predict patients’ survival in glioblastoma
The aggressive brain cancer is responsible for over 3,000 cases in the UK every year Researchers from King’s College London (KCL) have developed an
New programme shown to help dementia patients live independently
The neurodegenerative condition currently affects over 944,000 people in the UK A new programme led by Queen Mary University of London and funded by
NHS launches Pharmacy First to treat seven common conditions
Over 10,000 pharmacies in England will be offering the new advanced service The NHS has announced the launch of Pharmacy First, which allows patients
Pride and seek – PharmaTimes
A career in modern clinical research must attract diversity Many face a roadblock when shifting careers, encountering a catch-22 of needing experience for a
Happy Mondays – PharmaTimes
A company’s ability to continuously attract talent is a crucial part of its success. Significant global challenges in recent years however, have forced organisations
Dr Nicola Thompson – PharmaTimes
Camena has appointed Dr Nicola Thompson as Chair of its Board Camena Bioscience – a synthetic biology company providing genes to the pharmaceutical and
NHS launches BRCA testing programme for people of Jewish descent
Individuals with Jewish ancestry are six times more likely to carry a genetic fault The NHS has announced the launch of a new BRCA
Study reveals SARS-CoV-2 can infect dopamine neurons causing senescence
Dopamine neuron senescence is a hallmark of Parkinson’s disease Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Columbia University Vagelos College of Physicians
Cancer treatment could identify patients most likely to respond to cancer drugs
Tumours with high mtDNA mutations more likely to respond to Opdivo Scientists from the Cancer Research UK Scotland Institute and Memorial Sloan Kettering Cancer
Millions of people to view digital prescriptions via the NHS app
Prescriptions ordered via the app are expected to save around 1.85 million hours in 2024 NHS England has announced that its new digital prescription
Gavin Burns – PharmaTimes
Broken String has appointed Gavin Burns as VP of Quality and Operations Broken String Biosciences – a genomics company – has announced the appointment of Gavin Burns as
MRC Laboratory of Medical Sciences worth £120m opens on ICL campus
The institute is one of two UK laboratories wholly funded by the MRC The Medical Research Council (MRC) has opened a new Laboratory of
People with chest pain more likely to develop heart and circulatory diseases
Around one million adults in the UK visit their GP every year due to chest pain Researchers from Keele University have identified the key
International consortium identifies biomarkers for cardiovascular disease in diabetes
Type 2 diabetes is estimated to affect 462 million people worldwide An international academic consortium led by Johns Hopkins University, US, the Chinese University
NHS delivers a further 5,000 permanent hospital beds
A total of 103,277 general and acute beds are now available to NHS patients New figures have shown an increase of an additional 5,000
Study suggests heart stress test could transform patient diagnosis
The EST identified 30% of patients with a blood supply/demand mismatch Researchers from King’s College London (KCL) have revealed that the revival of a
Researchers identify gene that causes heart defects in Down syndrome
Around 50% of babies born with the condition are affected by heart defects Researchers from the Francis Crick Institute and University College London have
PlaqueTec and Babraham Institute partner for treatment of coronary heart disease
CAD is responsible for around 68,000 deaths per year in the UK PlaqueTec and the Babraham Institute’s Flow Cytometry facility have announced a collaboration
NHS urges more young people to take up HPV vaccine
HPV is a common group of viruses which can sometimes lead to cancer The NHS is urging both parents and young people between the
BHF data reveals early heart disease deaths rise to highest level
In 2022, over 39,000 people in England died prematurely of cardiovascular conditions The British Heart Foundation (BHF) has revealed new data showing that early
Middle of a chain reaction
The pharma industry is undergoing a profound transformation with the introduction of legislative reforms and the adoption of electronic patient information (ePI). Indeed, ePI
NHS to test new blood group genotyping test on inherited blood disorder patients
Patients living with sickle cell disease and thalassaemia will be eligible for the test The NHS has announced that it is the first healthcare
Calluna Pharma announces €75m series A financing for immunological diseases
The new company will develop novel therapies to benefit the body’s immune system Oxitope Pharma and Arxx Therapeutics have announced their merger to form
Researchers advance blood tests’ ability to detect cancer earlier
The advancement could allow earlier detection of cancer in the blood and better treatment Researchers from the Massachusetts Institute of Technology (MIT) and the
MIT researchers repurpose cancer compound to treat PKD
Autosomal dominant polycystic kidney disease affects more than 12 million people globally Researchers at the Massachusetts Institute of Technology (MIT) and Yale University School
Virtual reality training to help NHS doctors spot signs of sepsis
Approximately 48,000 deaths in the UK occur from sepsis every year The Great Western Hospitals NHS Foundation Trust has partnered with the training platform,
NHS catch up campaign launched for missed MMR vaccines
Approximately one in five children will be hospitalised to treat measles The NHS has announced the launch of its new catch up campaign to
Serac to present data from DETECT study
Company will present vital findings at SRI annual meeting Serac Healthcare – a clinical radiopharmaceutical company – has announced that an abstract on vital
Stroke experts to test emerging nerve stimulation treatment
New stroke therapy delivers electrical pulses to the brain A new stroke therapy which delivers electrical pulses to the brain via a portable, pacemaker-type
Synendos receives EMA nod for brain therapy
Company is focused on endocannabinoid system treatments Synendos Therapeutics – a company focused on innovative endocannabinoid system (ECS) treatments – has announced that it
UCB announces MHRA approval for UCB’s Zilbrysq
Green light concerns generalised myasthenia gravis therapy The Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation for Zilbrysq as an add-on
Poolbeg’s cytokine release syndrome drug shows potential
Data supports Poolbeg’s strategic expansion of POLB 001 Poolbeg – a company focused on innovative medicines – has announced promising in vivo results for
StemSight and ERS Genomics focus on collaboration
License agreement concerns development of cell therapies for corneal blindness ERS Genomics Limited (ERS) – a company formed to provide wider access to foundational
Aston University receives £10m for membrane institute
Aston University to create the Aston Institute for Membrane Excellence Aston University is on course to create the Aston Institute for Membrane Excellence (AIME)
Disco tunes into new cancer drug targets
EUR 20m to identify new targets and develop first in class drugs DISCO Pharmaceuticals – a company specialising in unlocking the surfaceome of cancer
Kanabo and City Dock Pharmacy team up
Companies collaborate to launch walk-in pain clinic Kanabo Group has linked up with City Dock Pharmacy in London, to introduce a walk-in pain clinic
CellVoyant secures £7.6 million AI stem cell boost
CellVoyant’s platform combines AI with live cell imaging CellVoyant – an AI biotechnology spin-out from the University of Bristol – has announced a £7.6
Vicore Pharma’s DTx to benefit pulmonary fibrosis patients
The nine-week DTxl CBT helps to address psychological symptom burdens in PF patients Vicore Pharma has announced positive results for its digital cognitive behavioural
Deepcell and NVIDIA collaborate to advance AI in single cell research
Both aim to advance the use of AI-powered cell analysis for cancer, stem cell and cell therapies Deepcell has entered into a research collaboration
Study reveals antibiotic use is not the only driver of antibiotic resistance
Researchers compared 20 years of antibiotic use on E. coli in the UK and Norway Researchers from the Wellcome Sanger Institute, the University of
Cambridge researchers begin new trial for oesophageal cancer screening
If successful, the new test could see routine screening introduced in the NHS Researchers at Cambridge University Hospitals NHS Foundation Trust and the University
Nightingale sings – PharmaTimes
New fleet of ultrasound machines at NHS Nightingale Hospital Exeter With a quarter of the population now on the NHS waiting list , reducing
Inhalable sensor to make lung cancer screening more accessible worldwide
The diagnostic system can deliver particles to the lungs via aerosol or a nebuliser Engineers from the Massachusetts Institute of Technology (MIT) have designed
New data reveals out-of-hospital cardiac survival results remain low in England
In 2022, around 8% of patients survived 30 days after a cardiac arrest New data published by the Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) Registry,
New clinical study to advance development of treatments for liver cirrhosis
The £30m ADVANCE study is the most extensive study into liver disease worldwide A new study involving Boehringer Ingelheim, Newcastle University and the University
Barinthus Bio announces $47m project to advance MERS coronavirus vaccine
The partnership will advance VTP-500 from early development to phase 2 clinical trials Barinthus Biotherapeutics has announced a new partnership with the Coalition for
Fertilised chicken eggs could be viable for use in cancer imaging research
The fertilised eggs could cultivate tumours for imaging within seven days Researchers from King’s College London (KCL) have identified that fertilised chicken eggs could
Nearly three million people received urgent NHS cancer checks in 2023
The number of people getting tested over the last decade has increased by 133% The NHS has announced a new analysis showing its highest
Owkin and Evotec partner to accelerate therapeutics in oncology and I&I
The companies will aim to select targets, discover and develop new therapeutics Owkin and Evotec have entered into an artificial intelligence (AI)-powered strategic partnership
Immune cell helps predict skin cancer patients’ responses to immunotherapies
Vd1-gd T cells were effective in predicting positive responses to ICI therapy Researchers from King’s College London (KCL), Guy’s and St Thomas’ Hospital Trust
Risk model predicts response and survival of cancer patients treated with ICIs
Metastatic cancer is estimated to be responsible for 90% of cancer deaths Researchers from the University of Eastern Finland and Kuopio University Hospital have
Disrupted sleep could be associated with cognitive function changes
High amounts of disrupted sleep were found to affect memory and thinking performance Researchers from the University of California have suggested an association between
AnX Robotica receives FDA clearance for small bowel capsule endoscopy technology
NaviCam ProScan is the first AI-assisted reading tool for gastrointestinal bleeding AnX Robotica has announced that the US Food and Drug Administration (FDA) has
Novo Nordisk to open new AI hub in UK for drug discovery
The new hub will be located in the King’s Cross Knowledge Quarter, London Novo Nordisk has announced its plans to open a new, artificial
Digital training programme improves quality of life for dementia patients living in care
The programme is the only remote, digital delivery nursing home training programme for dementia King’s College London and the University of Exeter have announced
Wearable technology to be offered to thousands with type 1 diabetes in UK
The condition affects around 270,935 people in England and 16,090 people in Wales The National Institute for Health and Care Excellence (NICE) has published
New study finds heathy cells ‘push’ cancer cells to resist treatment
Slow-growing cancer cells become more resistant to chemotherapy treatment Researchers from University College London (UCL) and Yale University have found that
ACSR to use digitised pathology for HIV-associated malignancies
The software has reduced the time to provide pathology data from days to hours The National Institutes of Health (NIH)-funded AIDS
















































































































